Is Perimenopause Throwing You Off? We've Got Answers! There’s not an organ in your body that isn’t impacted by menopause. (Seriously!) And because what is referred to as menopause is actually perimenopause—and can last years, even decades—it’s important to plan for this transition, and manage its impact on your body. Luckily, there is a lot you can do to help minimize any negative impacts.